โดย SinWiSuth » 25 ธ.ค. 2010, 23:42
ตอนนี้คงต้องอิง ADA 2010 แล้วล่ะนะครับ
ซึ่งมีปารปรับเปลี่ยนเกี่ยวกับแนวทางการให้ยาต้านเกร็ดเลือดไปจากเดิม
Antiplatelet agents
* Consider aspirin therapy (75?162 mg/day) as a primary prevention strategy in those with type 1 or type 2 diabetes at increased cardiovascular risk (10-year risk >10%). This includes most men >50 years of age or women >60 years of age who have at least one additional major risk factor (family history of CVD, hypertension, smoking, dyslipidemia, or albuminuria). (C)
* There is not sufficient evidence to recommend aspirin for primary prevention in lower risk individuals, such as men <50 years of age or women <60 years of age without other major risk factors. In patients in these age-groups with multiple other risk factors, clinical judgment is required. (C)
* Use aspirin therapy (75?162 mg/day) as a secondary prevention strategy in those with diabetes with a history of CVD. (A)
* For patients with CVD and documented aspirin allergy, clopidogrel (75 mg/day) should be used. (B)
* Combination therapy with ASA (75?162 mg/day) and clopidogrel (75 mg/day) is reasonable for up to a year after an acute coronary syndrome. (B)
http://care.diabetesjournals.org/conten ... _1/S4.full
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